Phenylpropanoids and polyketides
Cinnamic acids and derivatives
(938)
Flavonoids
(928)
Linear 1 3-diarylpropanoids
(804)
Coumarins and derivatives
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Depsides and depsidones
(521)
Phenylpropanoic acids
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Medchemexpress LLC 6-(4-(1-aminocyclobutyl)phenyl)-5-phenylnicotinamide | 1357158-81-6 | >98.0% | 343.42 g/mol | C22H21N3O | 10 MG
AKT-IN-1 is a small-molecule allosteric inhibitor of the AKT kinase family used for pathway and cancer research. It inhibits AKT with an IC50 of 1.042 μM, has CAS 1357158-81-6, and is supplied as a research-grade solid with high purity for biochemical and cellular assays.
- Allosteric AKT inhibition with IC50 = 1.042 μM.
- High chemical purity for reproducible results.
- Suitable for PI3K/Akt/mTOR pathway studies and cancer research.
- Solid form enabling flexible solution preparation.
- Molecular weight 343.42 g/mol and formula C22H21N3O for accurate dosing.
- Intended for research use only.
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Medchemexpress LLC 4'-Methoxychalcone | 959-23-9 | 99.8% | 5 G
4'-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. It also modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity. This product is intended for research use only.
- Regulates adipocyte differentiation via PPARγ activation
- Modulates adipokine expression and secretion involved in insulin sensitivity
- Increases mRNA expression of adipogenic genes during differentiation
- Reduces upregulated mRNA expression of IL-6, PAI-1, and MCP-1
- Causes an increase in PPARγ expression during differentiation
- Exhibits antiproliferative activity and cytotoxicity against various human cell lines
- Targets PPARγ
- Derived from Piperaceae Piper nigrum Linn.
- Classified as flavonoids, chalcones